Fig. 2

Chromatin peaks annotated to proximal promoters drive the correlation between normalized ATAC-seq and RNA counts. A Transcripts identified by RNA-seq were overlapped with chromatin peaks annotated to the same genes. The normalized ATAC- and RNA-seq counts were log scaled and analyzed using Pearson correlation analysis. B Overlapping ATAC- and RNA-seq counts from (A) were stratified by genomic feature. Pearson correlation analysis was used to identify feature-specific correlations between ATAC- and RNA-seq counts. Here, and in following figures, ns = not significant, *p < 0.05; **p < 0.01; ***p < 0.001