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Fig. 3 | BMC Genomics

Fig. 3

From: Harnessing changes in open chromatin determined by ATAC-seq to generate insulin-responsive reporter constructs

Fig. 3

Insulin induces differential chromatin accessibility and gene expression in S2 cells. A Volcano plot of differential chromatin accessibility in significantly different chromatin peaks, stratified by feature type. The dotted line represents FDR = 0.05. B) Proportions of genomic features annotated to chromatin peaks with differential accessibility after treatment with insulin or vehicle. C Volcano plot of differential gene expression in S2 cells after treatment with vehicle or insulin. Red indicates upregulated genes and blue indicates downregulated genes. The dotted line represents FDR = 0.05

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