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Fig. 5 | BMC Genomics

Fig. 5

From: Harnessing changes in open chromatin determined by ATAC-seq to generate insulin-responsive reporter constructs

Fig. 5

Significant insulin-induced changes in ATAC-seq indicates recruitment of enhancers for transcript regulation. A Significant log2 fold change values from differentially-accessible chromatin peaks and differentially-expressed transcripts were analyzed by Pearson correlation analysis. B Overlapping chromatin peaks and differentially-expressed genes from (A) were stratified by feature type and reveal that distal (1-2 kb) promoter accessibility is correlated with insulin-induced transcript changes

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