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Fig. 3 | BMC Genomics

Fig. 3

From: Effect of berberine on global modulation of lncRNAs and mRNAs expression profiles in patients with stable coronary heart disease

Fig. 3

Construction of protein-protein interaction network. A PPI network of SALL4, DDIT3, ESR1 and their interacting proteins. The red dots and green dots represent represent up-regulated and down-regulated DE mRNAs and TFs, respectively. Solid lines represent positive relationship and dash lines represent negative relationship; Line thickness represents combine score. B Network of Reactome pathways and enriched proteins. Blue diamond represents pathway; Red and green elipse represents up-regulated and down-regulated mRNAs, respectively. PPI, protein-protein interaction; DDIT3, DNA damage inducible transcript 3; SALL4, sal-like protein 4; ESR1, estrogen receptor alpha gene; TF, transcription factor

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