Skip to main content
Fig. 3 | BMC Genomics

Fig. 3

From: Stage-specific miRNAs regulate gene expression associated with growth, development and parasite-host interaction during the intra-mammalian migration of the zoonotic helminth parasite Fasciola hepatica

Fig. 3

Structure and expression of miRNA clusters of Fasciola hepatica miR-71 and miR-2. (a) Structural organisation of pre-miRNA sequences using RNAfold to reveal clustering of fhe-miR-71a-5p with fhe-miR-2a-3p, fhe-miR-2b-1-3p and fhe-miR-2e-5p/3p; fhe-miR-71b with fhe-miR-2c-3p, fhe-miR-2d-3p and fhe-miR-2f-3p; and fhe-miR-71c-5p with fhe-miR-2-3p. Each cluster is represented with the minimum free energy (MFE) and predicted thermodynamic ensemble (TDE) of the RNA folding. (b) Expression of miR-71 and miR-2 in respective clusters across life stages, Newly excysted juveniles 24h (NEJ), Immature flukes (Juvenile 21dpi) and Adult parasites. Data is presented as normalised reads (CPM) in log2, mean ± SD of triplicate biological samples.

Back to article page

BMC Genomics

ISSN: 1471-2164

Contact us