Fig. 5

Expression profile of 650 mRNAs and potential miRNA-mRNA networks construction. A, The heat map of 650 mRNAs. This heat map was constructed based on expression values of 650 miRNAs. The expression values from − 2 to 2 were depicted in line with the color scale representing the intensity increased from green to red. Three osteogenic induced groups and three control groups were included, each column represented one sample and each row indicated one transcript. B, Construction of potential miRNA–mRNA networks based on 21 miRNAs and 650 mRNAs by group type attributes layout exporting. C, Construction of potential miRNA–mRNA networks based on 21 miRNAs and 650 mRNAs by interaction attributes layout exporting. Bioinformatics software (http://www.bioinformatics.com.cn/) was used to create the maps in Fig. 5A. Cytoscape 3.9.0 software (https://cytoscape.org/) was used to create the maps in Fig. 5B ~ C