|
PRRs
|
109
|
nlrc3; nlrc5; nlrp1b; nlrp4e; trpm2; nod2; nwd1; spry2; spry3
|
pathogen recognition receptor; intracellular signal transduction [67, 68]
|
|
8
|
illr3; cd209; c209d
|
pathogen recognition receptor/sensing RNA viruses [69]
|
|
6
|
tlr1l; tlr2-1; tlr21; tlr22; tlr3; tlr9
|
pathogen recognition receptor/sensing RNA viruses [70,71,72]
|
|
1
|
ifih1
|
pathogen recognition receptor/sensing RNA viruses [73]
|
|
ISG
|
36
|
gimap7; gimap4; gimap8
|
secretion of cytokines; anti-apoptosis of lymphocytes [74]
|
|
9
|
gvinp1
|
Host resistance [75, 76]
|
|
1
|
mx
|
antiviral effector; inhibition of viral replication [77,78,79,80]
|
|
1
|
ifit2
|
inhibition of viral translation and replication [81, 82]
|
|
13
|
Nd
|
immunomodulator; antigen presentation [83,84,85]
|
|
30
|
trim2,9,25,32,33; bty; btr01,06; mid2
|
Sensors, restriction factors of viruses, regulators of IFN response [86, 87]
|
|
12
|
pkr1; prkrir; eif2ak2; thap4, 7; pak3,4
|
inhibition of viral translation and replication [88]
|
|
4
|
samhd1
|
Inhibition of viral replication [89]
|
|
1
|
sp100
|
inhibition of viral replication [88]
|
|
4
|
apo1; apol3
|
Degradation of the virus [88, 90, 91]
|
|
1
|
dram1
|
Degradation of the virus [86, 88, 92]
|
|
2
|
casp1; casp7
|
apoptosis effector [88]
|
|
3
|
stat5.1; stat6; Jak2
|
regulation of ISG expression [90, 93]
|
|
22
|
il17a/f-1; il20; il34; il1r1; il20ra; il6st
|
inflammation, protection against infection [94,95,96]
|
|
15
|
c1ql2; c1ql4l; c1qtnf1; tnfsf15; cd40
|
inflammation [97]
|
|
7
|
mavs; myd88; traf3; irf4; irf5; irf6; irf8
|
regulation of ISG expression [98,99,100]
|
|
101
|
rps2, 12, 14; wdr12; rpf2; nip7; eif4; eif4ebp3l; eif4a3; eif4ea; eif4b
|
inflammation, viral translation [98,99,100]
|
