Fig. 7

Identification of phospho-tyrosine consensuses in CD93 and Thrombomodulin. CD93 and Thrombomodulin phospho-tyrosine consensuses analysis. Positions of the amino acids are represented from the N- to the C-terminus in the x-axis and chemical properties of residues are color-coded. A Upper panel, CD93 phospho-tyrosine 1 (pY1) common consensus of all the  vertebrate clade (n = 68) residue frequencies are shown as probability rendering and expressed in bits. Lower panel, visualization of the CD93 second phospho-tyrosine (pY2) consensus in six vertebrate taxa. Sequences are shown as entropy rendering to emphasize motif’s information content. Number of species used for the analysis: Chondrichthyes n = 4, Neoteleostei n = 27, Marsupials n = 2 and Mammals n = 13. B Thrombomodulin phospho-tyrosine residue (pY) assessed independently for six vertebrate taxa: Teleosts n = 7, Amphibians n = 2, Birds n = 14, Marsupials n = 2 and Mammals n = 19. Sequences are shown as entropy rendering to emphasize motif’s information content