Fig. 1

The pathological features of RP mouse model. A Experimental design of the animal model. B Representative images of H&E and Masson’s trichrome staining of the rectal tissues in control (4 h) and radiation groups at each indicated time point. Scale bars, 100 μm. C Representative images of H&E and Masson’s trichrome staining of ARP, CRP lesions and normal colon tissue of human samples. Scale bars, 100 μm. The red arrows in B indicate mucosal glands inserted into the submucosa, and the red arrow head in B indicates vascular lesion