Fig. 6

Verification of the alteration of the hub genes by qRT-PCR analysis. A The mRNA expression levels of Cdk1, Ccna2, Aurkb, Aurka and Mki67 in the rectal tissues of mice in control and radiation groups at 4 h PI. B The mRNA expression levels of Mdm2, Cdkn1a, Bbc3, Bax and Sesn2 in the rectal tissues of mice in control and radiation groups at 1 day PI. C The mRNA expression levels of Tnf, Myc, Cd44, Col1a1 and Icam1 in the rectal tissues of mice in control and radiation groups at 3 days PI. D The mRNA expression levels of Fn1, Cdh5, Pecam1, Col1a1 and Mmp2 in the rectal tissues of mice in control and radiation groups at 2 weeks PI. E The mRNA expression levels of Fn1, Tnf, Alb, Il6 and Il1b in the rectal tissues of mice in control and radiation groups at 8 weeks PI. n = 3 for each time points. Data are shown as means ± SD. Statistical analyses were performed by unpaired Student’s t-test. ns, not significant. *p < 0.05, **p < 0.01, ***p < 0.001