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Fig. 7 | BMC Genomics

Fig. 7

From: From a large-scale genomic analysis of insertion sequences to insights into their regulatory roles in prokaryotes

Fig. 7

Evolutionary model of the IS-Gene couples. The arrows and rectangles correspond to genes and IS occurrences, respectively. The colored arrows are homologous genes. From the G1 block (set of genes including the IS and homologous and nonhomologous genes) (here G1), horizontal gene transfers (steps a1 and a2) and IS transposition events (steps b1 and b2) lead to the creation of a new block (here G2) in another genome. An IS deletion event can yield a unique (or nonsyntenic) IG (steps b3 and b4). During evolution, a given IS can be conserved through the evolutionary history leading to an observed syntenic IG (sIG) when an IS plays a positive role (i.e., regulatory motifs for neighboring genes) in the host genome (step a3). G1 or G2 blocks return to the starting point for new evolutionary events (steps a4–1 and a4–2)

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BMC Genomics

ISSN: 1471-2164

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