Transcriptional changes in the peripheral blood leukocytes from Brangus cattle before and after tick challenge with Rhipicephalus australis

Table 1 Top significant DEGs from the comparison between 3-week tick-exposed and tick-naive steers

Symbol	Entrez ID	Name	log₂FC^a	p-val	FDR^b
PROCR	282,005	protein C receptor	3.57	2.23E-04	4.34E-03
LOC104972252	104,972,252	uncharacterized LOC104972252	3.24	8.69E-04	9.71E-03
ESYT3	530,157	extended synaptotagmin 3	3.22	7.56E-05	2.39E-03
PDLIM1	614,675	PDZ and LIM domain 1	3.09	8.31E-06	7.37E-04
SMPD3	514,201	sphingomyelin phosphodiesterase 3	3.02	1.30E-03	1.22E-02
ALOX15	282,139	arachidonate 15-lipoxygenase	2.97	9.88E-03	4.67E-02
MFSD4A	515,128	major facilitator superfamily domain containing 4A	−3.05	1.01E-04	2.83E-03
GRO1	281,212	chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)	−3.08	1.45E-04	3.51E-03
LOC515150	515,150	apolipoprotein R	−3.13	2.57E-03	1.93E-02
FOS	280,795	Fos proto-oncogene, AP-1 transcription factor subunit	−3.13	2.96E-06	4.89E-04
KIAA1324L	518,313	KIAA1324 like	−3.23	5.54E-06	6.26E-04
MARCO	505,632	macrophage receptor with collagenous structure	−3.23	2.73E-03	2.00E-02

^a log₂FC represents the fold change in gene expression between 3-week tick-exposed (T3 sample set) and tick-naive steers (T0 sample set). Table displays genes above threshold |logFC| > 2.5
^b FDR represents the false discovery rate (Benjamini-Hochberg multiple test correction of the p-value). Table displays genes below threshold FDR < 0.05

ISSN: 1471-2164