Transcriptional changes in the peripheral blood leukocytes from Brangus cattle before and after tick challenge with Rhipicephalus australis

Table 4 Differentially expressed genes by tick infestation and host resistant phenotype

Symbol	Name	T3/T0^a	T12/T0^b	LR_T0/HR_T0^c	LR_T12/HR_T12^d
IL2RB	interleukin 2 receptor subunit beta	0.61		0.32
ITGB3	integrin subunit beta 3	1.22	1.36	− 0.40
CXCR5	C-X-C motif chemokine receptor 5	0.94	0.82	−0.43
C18H19orf18	chromosome 18 C19orf18 homolog	−0.85		−0.55
LTBP1	latent transforming growth factor beta binding protein 1	−1.42		−0.77
EHD3	EH domain containing 3		0.55	−0.33
GPR82	G protein-coupled receptor 82		0.66	−0.46
IL9R	interleukin 9 receptor		1.33	−0.64
SEMA3G	semaphorin 3G		1.30	−0.68
RAB27B	RAB27B, member RAS oncogene family		1.47	−0.91
BOLA-DRB2	histocompatibility complex, class II, DR beta 2	0.87	0.67		−1.15

^a T3/T0 represents the fold change in gene expression between 3-week tick-exposed and tick-naïve steers
^b T12/T0 represents the fold change in gene expression between 12-week tick-exposed and tick-naïve steers
^c LR_T0/HR_T0 represents the fold change in gene expression between low (LR) and high (HR) host resistance steers at pre-infestation
^c LR_T12/HR_T12 represents the fold change in gene expression between low (LR) and high (HR) host resistance steers at 12 weeks post-initial infestation

ISSN: 1471-2164