9-mer UL4015-23 (accession number) | (n) % patients | % OPT | Cleavage model predicteda | Binding Scoreb |
---|
LMAPRTLLL (9) | (1) 0.5 | 97.54 | Yes | 277.0 |
VIAPRTLIL (17) | (1) 0.5 | 90.85 | yes | 258.0 |
VLAPRTLLL (7) | (1) 0.5 | 95.42 | yes | 271.0 |
VMAPRILIL (4) | (2) 1 | 80.99 | yes | 230.0 |
VMAPRILVL (11) | (4) 2 | 80.28 | yes | 228.0 |
VMAPRSLIL (15) | (1) 0.5 | 87.68 | yes | 249.0 |
VMAPRSLLL (6) | (2) 1 | 89.44 | yes | 254.0 |
VMAPRTLFL(12) | (2) 1 | 91.90 | yes | 261.0 |
VMAPRTLIL (3) | (120) 60.3 | 98.24 | yes | 279.0 |
VMAPRTLIM (5) | (1) 0.5 | 94.01 | No | 267.0 |
VMAPRTLIV (18) | (1) 0.5 | 95.77 | yes | 272.0 |
VMAPRTLLL (1) | (20) 10 | 100 | yes | 284.0 |
VMAPRTLVL (2) | (36) 18 | 97.54 | yes | 277.0 |
VMDPRTLIL (13) | (1) 0.5 | 88.03 | yes | 250.0 |
VMGPRTLLL (14) | (1) 0.5 | 91.55 | yes | 260.0 |
VMTPRTLIL (19) | (1) 0.5 | 90.85 | yes | 258.0 |
VMTPRTLLL(10) | (1) 0.5 | 92.61 | yes | 263.0 |
VMTPRTLVL (8) | (2) 1 | 90.14 | yes | 256.0 |
VMVPRTLVL (16) | (1) 0.5 | 88.03 | yes | 250.0 |
- % OPT is the percentile score of the predicted peptide relative to that of the consensus. The consensus is the sequence that yields the maximum score, namely optimal score (OPT) with the selected profile. aProteasomal cleavage predictions was carried out using three optional models obtained applying statistical language models to a set of knwon epitopes restricted by human MHCI molecules. * The binding potential (score) of any peptide sequence (query) to a given MHCI is obtained by aligning the relevant PSSM with the protein segments, and adding up the profile scores that match the residue type and position in the profile. bBinding Score according to maximum score of 284 obtained with VMAPRTLLL. GenBank accession numbers: (1) OM397419, (2) OM397420, (3) OM397421, (4) OM397422, (5) OM397423, (6) OM397424, (7) OM397425, (8) OM397426, (9) OM397427, (10) OM397428, (11) OM397429, (12) OM397430, (13) OM397431, (14) OM397432, (15) OM397433, (16) OM397434, (17) OM397435, (18) OM397436, (19) OM397437.