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Fig. 2 | BMC Genomics

Fig. 2

From: Manipulating base quality scores enables variant calling from bisulfite sequencing alignments using conventional bayesian approaches

Fig. 2

Precision-sensitivity of variants called in real data. In response to an increasing variant quality (QUAL) threshold, SNPs derived from published WGBS data are compared to those derived from established benchmark datasets for AA. thaliana (Cvi-0) and B human (NA12878). Software with the epi- prefix are intended for conventional DNA sequencing libraries but in this case run after preprocessing with the double-masking procedure. True and false positives are evaluated based on both the substitution context and the estimated genotype

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