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Table 3 Mtb L4 sublineages identified by WGS

From: Whole genome sequencing analysis to evaluate the influence of T2DM on polymorphisms associated with drug resistance in M. tuberculosis

Sublineage

Code

T2DM isolatesa

TB isolatesb

Total

(n = 74)

(n = 74)

(n = 148)

PGG3

4.10

10 (13.5%)

19 (25.6%)

29 (19.5%)

X

4.1.1

3 (4.0%)

2 (2.7%)

5 (3.3%)

X2

4.1.1.1

0 (0.0%)

1 (1.3%)

1(.06)

X3/X1

4.1.1.3

10 (13.5%)

2 (2.7%)

12 (8.1%)

T1;H1

4.1.2

1 (1.3%)

2 (2.7%)

3 (2%)

Haarlem

4.1.2.1

18 (24.3%)

7 (9.4%)

25 (16.8%)

Ural

4.2.1

7 (9.4%)

17 (22.9%)

24 (16.2%)

LAM3

4.3.2

5 (6.7%)

0 (0.0%)

5 (3.3%)

LAM9

4.3.3

10 (13.5%)

21 (28.3%)

31 (20.9%)

LAM1

4.3.4.1

3 (4.0%)

1 (1.3%)

4 (2.7%)

LAM11

4.3.4.2

1 (1.3%)

4 (5.3%)

5 (3.3%)

S

4.4.1

1 (1.3%)

0 (0.0%)

1(.06)

  1. aT2DM: Host with diabetes mellitus type 2 and tuberculosis
  2. bTB Isolates: Host without diabetes mellitus type 2 and tuberculosis