Table 1 Amino acid specificity of detected PTMs in our study

Cysteine (C)

Nitrosylation, Ammonia loss, Carbamyl

Aspartate (D)

Carboxylation, Calcium, Fe [II], Sodium, Fe [III], Zinc, Potassium, Magnesium, Cu [I]

Glutamate (E)

Carboxylation, Calcium, Fe [II], Sodium, Fe [III], Zinc, Potassium, Magnesium, Cu [I], Water Loss

Lysine (K)

Methylation, Formylation, Hydroxylation, Trimethylation, Acetylation, Glutarylation, Succinylation, Butyrylation, Crotonylation, Malonylation, Dimethylation, Hydroxybutyrylation, Carboxylation, Pyridoxal phosphate, Carbamyl

Methionine (M)

Oxidation, Carbamyl

Asparagine (N)

Hydroxylation, Deamidation, Ammonia loss

Proline (P)

Hydroxylation

Glutamine (Q)

Deamidation

Arginine (R)

Citrullination, Methylation, Dimethylation, Carbamyl

Serine (S)

Phosphorylation, ADP-ribosylation, HexNAc

Threonine (T)

Phosphorylation, HexNAc

N-Terminal (X)

Acetylation, Carbamyl

Tyrosine (Y)

Sulfonation, Nitrosylation, Phosphorylation