Fig. 2
From: Cold exposure induces lipid dynamics and thermogenesis in brown adipose tissue of goats
KEGG pathway analysis of upregulated genes of BAT upon cold exposure. (A) Enrichment of Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways of cold-induced upregulated genes using KEGG database [16]; (B) cGMP-PKG (ko04022) and cAMP signaling pathway (ko04024) analysis was used by gene set enrichment analysis (GSEA) on RNA-seq data from RT and Cold group. The green line represented the enrichment of pathway in the Cold or RT group according to gene expression levels, with genes enriched in the Cold group shown on the left and genes enriched in the RT group shown on the right; (C-D) Heatmaps of the FPKM expression values of differentially expressed genes in cGMP-PKG signaling pathway and Citrate cycle (TCA cycle) after cold exposure. IRS1_x1 represented IRS1 isoform 1, and PRKG1_x2 represented PRKG1 isoform 2