Skip to main content
Fig. 1 | BMC Genomics

Fig. 1

From: Comprehensive analysis of RNA m6A methylation in pressure overload-induced cardiac hypertrophy

Fig. 1

Ventricular hypertrophy and reduced cardiac function were observed in mice after four weeks of transverse aortic constriction. A Representative image of mouse hearts in both groups; B–C Gravimetric analysis of heart weight normalized to body weight (HW/BW) and lung weight normalized to body weight (LW/BW) in both groups (n = 8 each); D–I Measurements of left ventricular posterior wall thickness at end-diastole (LVPW.d), left ventricular posterior wall thickness at end-systolic (LVPW.s), internal dimension at end-diastole (LVID.d), internal dimension at end-systolic (LVID.s), interventricular septal thickness at end-diastole (IVS.d), and interventricular septal thickness at end-systolic (IVS.s) in both groups (n = 8 each), respectively; J–K Echocardiographic ejection fraction (EF) and fractional shortening (FS) measurements in both groups (n = 8 each). The results are expressed as the means ± SD (*p < 0.05, **p < 0.01, compared to the Sham group)

Back to article page