Fig. 1
From: Detecting antibody reactivities in Phage ImmunoPrecipitation Sequencing data
Average receiver operating characteristic (ROC; top panels) and precision-recall (PR; bottom panels) curves calculated from ten simulations, comparing edgeR (black lines) and BEER (red lines) across fold-change categories and number of beads-only samples available. Curves for BEER using the actual simulation shape parameters in the prior distributions (orange lines) are added to show the effect of sampling variability in these parameters. Results for fold changes above 16 are omitted since in all instances peptides were correctly classified as enriched