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Fig. 3 | BMC Genomics

Fig. 3

From: Transcriptomic profiles of muscular dystrophy with myositis (mdm) in extensor digitorum longus, psoas, and soleus muscles from mice

Fig. 3

a K-means clustering of 6980 differentially expressed genes (p-adj < 0.01; absolute log2 fold change >  = 1) identified from mdm vs wild type comparisons in EDL, psoas and soleus. b Top 5 GO terms associated with each cluster, when sorted by adjusted P-value (shown at right to each bar). Each cell in the clustering heatmap is colored based on the respective Z-value associated with cluster mean. Red = higher expression levels compared to mean expression of gene; Blue = lower expression levels compared to the mean expression of the gene. Optimal number of k-means clusters was determined as 11 based on the maximum gap statistics and minimum within sum of square values calculated for k = 1 to k = 20 (insets)

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