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Fig. 5 | BMC Genomics

Fig. 5

From: A conserved transcriptional fingerprint of multi-neurotransmitter neurons necessary for social behavior

Fig. 5

vTely321 “transcriptomic fingerprint” is evolutionarily conserved. A Single cell RNA-sequencing data from Atlas of Zebrafish Development plotted using Uniform Manifold Approximation and Projection (UMAP) algorithm. The atlas consists of 220 computationally identified clusters and each of the clusters were annotated using cell-type information from previously identified marker genes from the Zebrafish Information Network (ZIFN). B “Transcriptomic fingerprint” expressed genes map onto Cluster 25 of the Atlas and their expression is plotted in UMAP space. Vgat expression in Cluster 25 included as a corroboratory marker. C Search results from the mousebrain.org online scRNAseq Atlas show that combined expression of Lhx6, Isl1, Lhx8, Gad1 and Chat maps onto telencephalic (TECHO) and diencephalic (DECHO1) clusters in the mouse brain. Other cholinergic clusters HBCHO1–4, MBCHO4, and DECHO2 do not express the full transcriptomic fingerprint

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