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Table 1 Demographic summary for 12 common infections

From: Genome-wide association analyses of common infections in a large practice-based biobank

Phenotype

Status

N

Female

Male

Age (years, mean ± SD)

EHR length (years, mean ± SD)

Streptococcal pharyngitis

Control

9970

6290

3680

31.8 ± 20.8

14 ± 6.8

Case

997

617

380

30.7 ± 21

13.9 ± 5.8

Candidiasis

Control

11,010

6911

4099

51.2 ± 22.6

13 ± 7.4

Case

2202

1385

817

52.9 ± 21.6

13.1 ± 7.4

Herpes zoster

Control

7510

4669

2841

65.8 ± 15.8

15.4 ± 7.1

Case

751

455

296

66.4 ± 15.7

15.3 ± 6.7

Hepatitis B

Control

2230

710

1520

57.3 ± 19.9

14.6 ± 7.4

Case

223

68

155

56 ± 14.7

14 ± 7.6

UTI

Control

46,795

26,484

20,311

53.5 ± 21.1

10.8 ± 7.1

Case

9359

6889

2470

59.3 ± 21.2

13.8 ± 7.2

Pneumonia

Control

31,925

15,125

16,800

58.5 ± 21.1

11.8 ± 7.4

Case

6385

3071

3314

58.8 ± 21.9

11.9 ± 7.5

Infectious mononucleosis

Control

1160

740

420

28.8 ± 18.7

13.9 ± 7.2

Case

116

70

46

28.3 ± 16.3

13.7 ± 6.5

Tuberculosis or a positive TB test

Control

1020

597

423

56.1 ± 19.1

14.3 ± 6.8

Case

102

56

46

56 ± 16.9

14.2 ± 6.5

Otitis media

Control

12,170

6879

5291

35.3 ± 22.8

13.8 ± 7.1

Case

2434

1299

1135

32.3 ± 25.6

13.3 ± 6.3

Chronic sinus infection

Control

12,860

7969

4891

58.4 ± 18.6

15.4 ± 6.7

Case

2572

1577

995

58.4 ± 17.6

15.5 ± 6.6

Hepatitis C

Control

6300

2211

4089

54.9 ± 20.4

12.3 ± 7.7

Case

1260

456

804

55.5 ± 12.9

12.3 ± 7.8

Herpes labialis

Control

3560

2142

1418

51.6 ± 21.4

15.2 ± 7.1

Case

356

223

133

51.3 ± 18.7

15.2 ± 6.9