Table 4 Significant associations between genetically-determined gene expression and common infections
From: Genome-wide association analyses of common infections in a large practice-based biobank
Phenotype | Tissue | gene_name | zscore | Effect size | P value | var_g* | n_snps_used# |
|---|---|---|---|---|---|---|---|
Otitis media | Brain_Nucleus_accumbens_basal_ganglia | SLC30A9 | 4.93 | 1.03 | 8.06E-07 | 0.014934 | 2 |
Candidiasis | Esophagus_Mucosa | LRP3 | 5.68 | 2.13 | 1.34E-08 | 0.005041 | 2 |
Liver | WDR88 | 5.54 | 0.55 | 3.11E-08 | 0.060999 | 1 | |
Brain_Spinal_cord_cervical_c-1 | LRP3 | 5.17 | 6.50 | 2.34E-07 | 0.000383 | 2 | |
Artery_Coronary | LRP3 | 5.13 | 2.67 | 2.82E-07 | 0.0029 | 2 | |
Spleen | LRP3 | 5.09 | 2.04 | 3.57E-07 | 0.004629 | 2 | |
Prostate | LRP3 | 5.07 | 3.39 | 3.91E-07 | 0.001917 | 1 | |
Adrenal_Gland | LRP3 | 5.07 | 2.33 | 3.91E-07 | 0.003467 | 1 | |
Minor_Salivary_Gland | LRP3 | 5.07 | 2.36 | 3.91E-07 | 0.003164 | 1 | |
Brain_Cortex | WDR88 | 4.76 | 0.39 | 1.95E-06 | 0.087545 | 1 | |
Hepatitis B | Heart_Atrial_Appendage | AAMDC | -4.81 | -2.59 | 1.51E-06 | 0.019472 | 3 |
Skin_Not_Sun_Exposed_Suprapubic | AAMDC | -4.89 | -3.35 | 1.02E-06 | 0.015421 | 3 |