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Fig. 3 | BMC Genomics

Fig. 3

From: Transcription and proteome changes involved in re-innervation muscle following nerve crush in rats

Fig. 3

Network analysis of transcriptome and proteome. a, b, c, d Analysis of KEGG pathway enrichment in DEGs (a, b) and DEPs (c, d). Rich factor refers to the ratio of the number of DEGs (or DEPs) in the pathway entry to the total number of genes (or proteins) in that pathway entry. Pathways were considered significantly enriched when P < 0.05. e, f Short time-series expression miner (STEM) clustering of DEGs (Fig. e) and DEPs (Fig. f). Each square represents the expression trend of a gene (or protein) in the control, DN and RN groups. The black polygonal line in the square indicates the overall expression profile of all DEGs (or DEPs) in the corresponding set. The profile ID and the number of DEGs and DEPs in each profile are shown on the top of the square. Colored squares are significantly different (P < 0.05). DEPs involved in the energy metabolic pathway were mainly distributed in the expression patterns of profiles 5 in STEM analysis

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