From: Leveraging family history in genetic association analyses of binary traits
Causal SNP minor allele frequency | CC-GWAS | LT-FH | Fam-meta | ||
---|---|---|---|---|---|
Power | Increase from CC-GWAS | Power | Increase from CC-GWAS | ||
0.01 | 0.742 | 0.770 | 0.028 | 0.786 | 0.044 |
0.02 | 0.718 | 0.757 | 0.039 | 0.774 | 0.056 |
0.05 | 0.696 | 0.750 | 0.054 | 0.767 | 0.071 |
0.10 | 0.667 | 0.732 | 0.065 | 0.750 | 0.083 |
0.20 | 0.656 | 0.716 | 0.060 | 0.737 | 0.081 |
0.30 | 0.658 | 0.714 | 0.056 | 0.739 | 0.081 |
0.40 | 0.639 | 0.707 | 0.068 | 0.729 | 0.090 |
0.50 | 0.620 | 0.689 | 0.069 | 0.707 | 0.087 |