From: Leveraging family history in genetic association analyses of binary traits
CC-GWAS | LT-FH | Fam-meta | ||||||
---|---|---|---|---|---|---|---|---|
rsIDs (Chr:b37Pos Mb) | Effect Allele and Frequency | Closest Gene Label | t-statistic | P-value | t-statistic | P-value | Tmeta | P-value |
rs7903146 (10:114.8) | T (0.31) | TCF7L2 | 6.69 | 2.3 × 10–11 | 7.04 | 2.0 × 10–12 | 6.92 | 4.5 × 10–12 |
rs78825768 (5:178.7) | C (0.048) | ADAMTS2 | 5.70 | 1.2 × 10–8 | 4.53 | 6.0 × 10–6 | 5.72 | 1.1 × 10–8 |
rs150003225 (5:119.7) | C (0.012) | PRR16 | 5.69 | 1.3 × 10–8 | 5.02 | 5.1 × 10–7 | 5.53 | 3.2 × 10–8 |
rs78855997 (13:94.2) | G (0.010) | GPC6 | 5.51 | 3.5 × 10–8 | 4.20 | 2.6 × 10–5 | 5.23 | 1.7 × 10–7 |
rs2383208 (9:22.1) | G (0.18) | CDKN2B-AS1 | -4.15 | 3.4 × 10–5 | -4.50 | 6.8 × 10–6 | -4.18 | 2.9 × 10–5 |
rs10830963 (11:92.7) | G (0.27) | MTNR1B | 3.84 | 1.2 × 10–4 | 2.53 | 1.1 × 10–2 | 3.68 | 2.4 × 10–4 |