Fig. 3

Differential expression analysis within structures. The number of differentially expressed (DE) genes (left) and their overlap (right) is displayed for each pairwise comparison in the medial preoptic area (MPOA, A), nucleus accumbens (NAc, B), and lateral septum (LS, C). On the right, UpSet plots [36, 37] depict the intersections between each set (pairwise comparison) of differentially expressed (DE) genes as matrix of dots with each row corresponding to a set and each column corresponding to a possible intersection. Dots are colored in grey when the given set (row) is not included in the given intersection (column), or in black when it is included. Joined black dots depict the overlap between given sets. For instance, a total of 164 genes were found DE between Mothers and Attackers in the MPOA (A, left). Among these 164 DE genes, 82 are unique to the Mothers vs Attackers comparison, 23 are also found DE in the Mothers vs Fathers comparison, 11 are also found DE in the Mothers vs Paternal comparison, and 48 are also found DE in the Mothers vs Paternal as well as Mothers vs Fathers comparisons (A, right). *p < 0.05, ***p < 0.001, hypergeometric test for overlaps between two or three sets of genes