Fig. 1

DEGs stimulated by ZIKV for 24 h. a DEGs in placental cells (JEG-3), nerve cells (U-251 MG), and kidney cells (HK-2). b DEGs stimulated by ZIKV for 24 h in JEG-3. c DEGs stimulated by ZIKV for 24 h in U-251 MG. d DEGs stimulated by ZIKV for 24 h in HK-2. Red and blue dots correspond to up-regulated and down-regulated genes, respectively. The top 10 up-regulated and down-regulated genes were determined by FC value and marked in the figures. Several labeled genes are not shown in the figures due to their overlap with other genes. JEG-3, U-251 MG, and HK-2 cells were infected with ZIKV African strain MR766 (MOI = 1). The control samples were the corresponding cells without ZIKV infections. The two-tailed student’s t-test was used in the detection of the DEGs between corresponding infected cells and uninfected cells. Each experiment was repeated for 3 times