Fig. 6

The enriched KEGG pathway of DEGs in placental cells at different time points. a The enriched KEGG pathway of DEGs in JEG-3 cells at 3 h post ZIKV infection. b The enriched KEGG pathway of DEGs in JEG-3 cells at 24 h post ZIKV infection. The DEGs at 12 h.p.i. failed to enrich at any KEGG pathway, thus not shown. Enrichment analyses were performed by clusterProfiler package of R software. Hypergeometric tests were used to screen enriched KEGG pathways, and P-values were further adjusted by the default “Holm” method. Those KEGG pathways with an adjusted P-value < 0.05 were considered significant. Here, the top 30 significant pathways ranked by adjusted p-value were displayed