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Fig. 2 | BMC Genomics

Fig. 2

From: Association of mTORC1‑dependent circulating protein levels with cataract formation: a mendelian randomization study

Fig. 2

Key assumptions and flow chat of Mendelian randomization study (This MR study fulfilled the three core assumptions: (1) IVs must be associated with exposure, (2) genetic instrument must not be associated with confounders, (3) must be no association between genetic instruments and cataract except through exposure. SNP, single nucleotide polymorphism; RP-S6K, ribosomal protein S6K kinase; EIF4EBP, eukaryotic initiation factor 4E-binding protein; EIF-4G, translation initiation factor 4G; EIF-4E, translation initiation factor 4E; EIF-4A, translation initiation factor 4A.)

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BMC Genomics

ISSN: 1471-2164

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