Fig. 2

Level 1 multi-organ comparison summary. A Venn diagram of upregulated imprinted genes in the brain in Mouse Cell Atlas and in the brain (non-myeloid) in the Tabula Muris. Imprinted genes are listed which show significant upregulation (q ≤ 0.05 and Log2FC ≥ 1) in the tissues. Although these tissues are not identical, they were the two brain associated over-representations in the enrichment analysis. Parental-bias is indicated by colour (MEG—red, PEG—blue). From the 119 imprinted genes in the gene list, only 92 were common to both analyses (i.e., successfully sequenced and passed gene quality control filters). 34 imprinted genes were upregulated in the brain in the MCA and 31 genes in the TM. Genes in common from the two analyses are presented in bold and totalled in each section of the Venn Diagram, while genes found upregulated in one analysis but not available in the other analysis are included in small font and the number indicated in brackets. B Tissues with over-representation in MCA, and C tissues with over-representation in Tabula Muris. For both coloured bold labels were over-represented tissues using all imprinted genes; tissues with a blue circle behind were over-represented for PEGs alone; a red circle represented over-representation for MEGs along; and a red/blue split circle were over-represented for both PEGs and MEGs