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Table 2 Imprinted gene over-representation in Tabula Muris adult tissues [28]

From: Systematic investigation of imprinted gene expression and enrichment in the mouse brain explored at single-cell resolution

Tissue Identity

Up Reg

(20,839)

IG

(107)

ORA

p

ORA

q

Mean FC

IG

Mean FC

Rest

GSEA

p

GSEA

q

No. IGs with highest expression

Diaphragm

416

19

3.66E-13

4.75E-12

6.49

4.83

0.1898

0.3796

4

Limb Muscle

761

24

6.32E-13

8.22E-12

9.02

5.09

0.0552

0.1104

8

Pancreas

4104

43

8.31E-07

1.08E-05

12.52

12.60

-

-

29

Trachea

1979

25

1.78E-05

0.0002

3.81

4.57

-

-

5

Brain (Non-Myeloid)

3081

31

0.0001

0.0016

12.16

14.17

-

-

14

Bladder

3338

31

0.0005

0.0068

3.30

5.30

-

-

16

 Fat

1263

12

0.0286

0.3713

3.46

3.68

-

-

1

 Heart

1108

10

0.0585

0.7601

2.87

5.14

-

-

0

 Mammary Gland

1826

12

0.2264

1

3.52

5.24

-

-

3

 Liver

1808

7

0.8307

1

6.19

54.93

-

-

3

 Aorta

3515

14

0.8832

1

7.47

16.08

-

-

2

 Tongue

4295

15

0.9696

1

4.15

7.16

-

-

8

 Large Intestine

4758

11

0.9998

1

5.95

12.22

-

-

5

 Brain (Myeloid)

1024

5

-

-

3.39

6.80

-

-

2

 Kidney

584

3

-

-

24.94

22.90

-

-

1

 Lung

914

2

-

-

2.73

5.41

-

-

0

 Marrow

1957

5

-

-

7.65

5.25

-

-

4

 Skin

1612

4

-

-

4.15

8.36

-

-

1

 Spleen

625

1

-

-

4.63

4.28

-

-

0

 Thymus

678

4

-

-

3.46

7.45

-

-

1

  1. All other column descriptions can be found in the legend of Table 1
  2. GSEA pp value from Gene Set Enrichment Analysis for identity groups with 15 + IGs and Mean FC IG > Mean FC Rest, GSEA q – Bonferroni corrected p values from GSEA.