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Table 5 Imprinted gene over-representation in nervous system region [31]

From: Systematic investigation of imprinted gene expression and enrichment in the mouse brain explored at single-cell resolution

Brain Region Identity

Up Reg

(18,335)

IG

(106)

ORA p

ORA q

Mean FC

IG

Mean FC

Rest

GSEA

p

GSEA

q

No. IGs with highest expression

Medulla

3147

45

8.38E-10

1.26E-08

4.79

4.01

0.1

0.2

15

Hypothalamus

1040

22

9.81E-08

1.47E-06

4.92

5.84

-

-

8

Pons

3581

44

1.62E-07

2.43E-06

4.20

3.91

0.1169

0.2338

22

Vent. Midbrain

1228

18

0.0002

0.0034

4.90

4.99

-

-

3

 Vent. Striatum

689

8

0.0463

0.6941

3.92

4.92

-

-

0

 Posterior Cortex

1090

9

0.1788

1

2.64

3.20

-

-

2

 Enteric Nervous System

3885

26

0.2311

1

8.98

121.04

-

-

11

 Sympathetic Nervous System

2804

18

0.3535

1

11.37

57.96

-

-

9

 Anterior Cortex

979

6

0.5016

1

2.72

3.30

-

-

1

 Dors. Midbrain

1045

6

0.5663

1

2.20

4.85

-

-

3

 Thalamus

1441

8

0.6000

1

2.90

6.36

-

-

0

 Hippocampus—CA1

1082

6

0.6008

1

3.01

4.02

-

-

2

 Somatosensory Cortex

2121

11

0.6943

1

4.09

3.70

-

-

8

 Dors. Striatum

1196

6

0.6974

1

4.03

5.43

-

-

2

 Dorsal Root Ganglion

3607

16

0.9088

1

11.56

75.89

-

-

9

 Middle Cortex

623

5

-

-

3.29

3.24

-

-

0

 Spinal Cord

972

5

-

-

4.57

12.36

-

-

1

 Amygdala

452

4

-

-

4.65

4.11

-

-

2

 Dentate Gyrus

796

4

-

-

3.79

4.16

-

-

2

 Hippocampus

631

4

-

-

4.86

3.82

-

-

2

 Olfactory Bulb

445

4

-

-

4.02

8.27

-

-

2

 Antero-Middle Cortex

646

3

-

-

4.59

4.31

-

-

1

 Cerebellum

240

0

-

-

0.00

32.30

-

-

0

  1. Nervous system regional identities for the cells used in analysis genes. All other column descriptions can be found in the legend of Tables 1 and 2