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Fig. 7 | BMC Genomics

Fig. 7

From: Identification and characterization of non-coding RNA networks in infected macrophages revealing the pathogenesis of F. nucleatum-associated diseases

Fig. 7

Dysregulated function analysis of ceRNA interaction networks during F. nucleatum infection. A The ceRNA network of lncRNAs/circRNAs-miRNAs-mRNAs significantly participated in GO:0006915(apoptotic process), GO:0043066(negative regulation of apoptotic), GO:0007155(cell adhesion), GO:0030154(cell differentiation), GO:0006629(lipid metabolic process), GO:0016192(vesicle-mediated transport), GO:0005925 (focal adhesion), GO:0070062(extracellular exosome), GO:0007049(cell cycle) and GO:0030054(cell junction). B The ceRNA network of lncRNAs/circRNAs-miRNAs-mRNAs significantly participated in insulin resistance, pathways in cancer, focal adhesion, platelet activation, chemokine signaling pathway, MAPK signaling pathway, cell cycle, TNF signaling pathway, Jak-STAT signaling pathway, apoptosis, Toll-like receptor signaling pathway and Vascular smooth muscle contraction. Square nodes represent mRNAs; Circular nodes represent miRNAs; Regular triangle nodes represent lncRNAs; V-shape nodes represent circRNAs; Blue diamond nodes represent GO terms; Yellow diamond nodes represent KEGG pathways. Red shows up-regulation and green shows down-regulation

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