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Table 2 Functional annotation clustering summary of temporal expressional change

From: In the battle of the disease: a transcriptomic analysis of European foulbrood-diseased larvae of the Western honey bee (Apis mellifera)

GROUP

TOTAL

TERM

Unique Control

7

GO:0005506 ~ iron ion binding

ame00030:Pentose phosphate pathway

ame00520:Amino sugar and nucleotide sugar metabolism

ame00561:Glycerolipid metabolism

ame00670:One carbon pool by folate

ame04142:Lysosome

ame04512:ECM-receptor interaction

Controls + Infected overlap

12

GO:0005576 ~ extracellular region

GO:0006030 ~ chitin metabolic process

GO:0006633 ~ fatty acid biosynthetic process

GO:0008061 ~ chitin binding

GO:0016021 ~ integral component of membrane

GO:0020037 ~ heme binding

GO:0042302 ~ structural constituent of cuticle

ame00010:Glycolysis / Gluconeogenesis

ame01100:Metabolic pathways

ame01130:Biosynthesis of antibiotics

ame01200:Carbon metabolism

ame01230:Biosynthesis of amino acids

Unique Infected

4

GO:0005215 ~ transporter activity

GO:0045087 ~ innate immune response

ame00260:Glycine, serine and threonine metabolism

ame00620:Pyruvate metabolism

  1. Control larvae (Cont 3 dpi vs. Cont 6 dpi), M. plutonius-infected larvae (Inf 3 dpi vs. Inf 6 dpi) and overlapping significant GO- and KEGG-pathway terms (p < 0.1, FDR-corrected). For more details on FAC see Table S 2 (Additional file 4) and Fig. S11 (Additional file 2)