Fig. 9

Functional analysis of proteins more abundant in vivo than in vitro at each developmental stage. The Metascape heatmap plots represent the top 20 clusters of enriched GO terms of biological processes and KEGG pathways (A), molecular functions (B), and cellular components (C). Each row represents one enriched cluster, and the orange gradation reflects statistical significance (the darker the color, the more significant the p-value is). Gray color indicates a lack of significance. DAPs with a t-test p-value ≤ 0.05 and fold-change ratio ≥ 1.5 were considered