Fig. 1
From: Analysis of differentially expressed long non-coding RNAs in LPS-induced human HMC3 microglial cells
Workflow and identification of DElncRNAs. A Schematic summarizing project workflow. B Volcano plots visualizing the effects of LPS and/or JQ1 on the lncRNA levels in HMC3 human microglial cells; the treatments were performed in triplicates and the combined results are shown. The gray vertical dot lines indicate log2 FC of ≥ 1.2 and ≤ -1.2. The gray horizontal dot lines indicate –log(padj) ≤ 0.01. C Heat map showing the expression changes of the 5 LPS-induced lncRNAs that qualified as DElncRNAs by the criteria of this study (see Materials and methods), and the heat maps for the same DElncRNAs upon treatment with JQ1 or LPS + JQ1. The color scale represents the log2 FC values. DElncRNAs; differentially expressed lncRNAs, DEmRNAs; differentially expressed mRNAs, log2 FC; log2 fold change, GO; Gene Ontology, KEGG; Kyoto Encyclopedia of Genes and Genomes