Table 2 Major networks and proteins obtained by IPA analysis of differentially expressed proteins in sepsis group
Top diseases and functions | Molecules in network | Score focus | Molecules |
|---|---|---|---|
Energy Production, Nucleic Acid Metabolism, Small Molecule Biochemistry | ADCY, AKT1, c-Src, CAMK2N1, caspase, CAV1, Cg, Creb, cytochrome, DBI, DHX15, FHIT, HDLBP, Hsp70, Hsp90, HSPE1, INPP5K, Lh, MAP2K1/2, MAVS, Mek, MTDH, MTX2, NAP1L1, NFkB (complex), PP2A, RALGAPB, Secretase gamma, SLC7A5, Sod, SOD1, SRP14, SRP54, USP47, VDAC1 | 42 | 20 |
Neurological Disease, Gastrointestinal Disease, Hepatic System Disease | A2M, Alp, AMPK, APOA1, calpain, CDH2, chymotrypsin, Collagen Alpha1, CTNND2, ERK1/2, Ferritin, GC, GPD2, HDL, HDL-cholesterol, hemoglobin, HP, HPX, JINK1/2, LDL, MAP4, NAA25, OSBPL8, p70 S6k, PDGF BB, PI3K (family), Pro-inflammatory Cytokine, SEPT6, SIK3, SLC12A2, Smad2/3, Tgf beta,TGM2, trypsin, UGGT1 | 31 | 16 |