Fig. 4
From: peaksat: an R package for ChIP-seq peak saturation analysis
Similar binding profiles between H4K5ac and H4K8ac. A Differential binding peaks across cell lines for H4K5ac and H4K8ac are combined together and grouped into 2 clusters to show the altered binding profiles and peak enrichment during progression cell models. The y-axis shows the different peaks and x-axis show the sites around the peak summit. RPM, reads per million, is scaled to indicate the enrichment signal. B Overall enrichment profiles of differential binding sites centered at peak summit for both targets across different cell lines. The clusters are the same as that in Fig. 4A. C Examples of genes nearest to the peaks in cluster 1 and cluster 2. Green peaks refer to H4K5ac binding sites, and orange peaks refer to H4K8ac binding sites. The arrows indicate the transcription direction (strand) for each example gene