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Fig. 3 | BMC Genomics

Fig. 3

From: Pulmonary artery embolism: comprehensive transcriptomic analysis in understanding the pathogenic mechanisms of the disease

Fig. 3

Expression profiles overview of pulmonary embolism. A Graphical representation of the first (PC1) and second (PC2) principal components distributed the sample expression pattern of pulmonary arteries affected by embolism (PA-E; n = 6) and control (CTR; n = 5) libraries. B MA chart with logarithmic values of fold change (logFC; Y axis) plotted against normalised counts (X axis) for PA-E and CTR libraries. C Volcano plot shows log2FC plotted against negative logarithmic adjusted p-values. The dotted horizontal line indicates a negative logarithmic adjusted p-value (0.05) cut-off. (B, C) Red dots represent upregulated differentially expressed transcribed active regions (TARs); green dots depict downregulated TARs; black dots are not significant transcripts, according to DESeq2 method

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BMC Genomics

ISSN: 1471-2164

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