ECA | Region (Mb) | Top 0.1% SNPs (n) | CSS value | Cluster rank | Candidate genes | Gene function |
---|---|---|---|---|---|---|
1 | 119.28–119.72 | 88 | 2.83 | 1 | CSPG4, PEAK1 | Matrix metalloproteinase 2 activity |
SEMA7A, CSK, PSTPIP1 | Rheumatoid arthritis | |||||
7 | 16.77–17.08 | 56 | 2.71 | 2 | GUCY1A2 | Rheumatoid arthritis |
EXPH5 | Inherited Skin Fragility | |||||
3 | 39.62–40.1 | 65 | 2.50 | 3 | EMCN | Rheumatoid arthritis |
3 | 20.14–21.01 | 104 | 2.34 | 5 | WWP2 | Plantar fibromatosis |
TERF2 | Dyskeratosis congenita | |||||
PSMD7 | Ankylosing spondylitis | |||||
NQO1 | Injury and inflammation | |||||
NOB1 | Osteosarcoma | |||||
NFAT5 | Inflammatory arthritis | |||||
HAS3 | Hyaluronan metabolism in human keratinocytes and atopic dermatitis skin | |||||
31 | 12.94–13.16 | 53 | 2.28 | 6 | OPRM1 | Rheumatoid Arthritis |