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Fig. 4 | BMC Genomics

Fig. 4

From: Tolerance to dietary linalool primarily involves co-expression of cytochrome P450s and cuticular proteins in Pagiophloeus tsushimanus (Coleoptera: Curculionidae) larvae using SMRT sequencing and RNA-seq

Fig. 4

Identification of transcription factors (TFs) involved in regulation of cytochrome P450 (CYP450) and cuticular protein (CP) genes. (a) Statistics of TF family. (b, d) Co-expression networks between TFs and CYP450 genes, TFs and CP genes using Pearson correlation coefficient. Rectangle and circular nodes indicate target mRNAs (i.e. CYP450 or CP) and DELncRNAs, respectively. Red and blue lines indicate positive and negative correlations, respectively. The TFs with top-ranked degrees are colored red. (c, e) Heatmap of hub TFs ranked by degrees. Data are shown as the average values of expression for each group, and are Z-score normalized across each row. Red bars indicate up-regulated TFs while blue bars indicate down-regulated TFs

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