Fig. 2

STRING-generated interaction network among selected enriched KEGG pathways. The network image shows interactions between proteins encoded by DEGs identified in the following KEGG molecular pathways: PI3K-Akt signaling pathway (ssc04151), prolactin signaling pathway (ssc04917), JAK-STAT signaling pathway (ssc04630), protein processing in endoplasmic reticulum (ssc04141) and phagosome (ssc04145). Clusters of genes/proteins within specific KEGG pathways are indicated in boxes and by corresponding colored nodes in the network image. Bold = up-regulated genes; Plain text = down-regulated genes in T20 vs CTL gilts. The thickness of the lines represents the confidence prediction of the interaction between 2 genes (thinnest: confidence 0.400; medium: confidence 0.700; thickest: confidence 0.900). Nodes with no interaction with other nodes were deleted. The interaction score was set at > 0.400 and KEGG pathway enrichment significance at P > 0.05 (FDR Benjamini-Hochberg)