Fig. 2

 A. The identification of 41 differentially expressed transcription factors (DETFs) based on comparison of 10,245 E. granulosus genes, along with 394 of E. granulosus transcription factors (TFs) and 818 differentially expressed genes in the early strobilar development of E. granulosus protoscoleces. B. Heatmap clustering of 41 differentially expressed TFs of E. granulosus according to RNA-seq data (Debarba et al., 2020). Pepsin-treated protoscoleces (PEP, 0 h), Pepsin-treated protoscoleces after 12 (12 h) and 24 h (24 h). The Z-score calculation on fold changes was utilized. C. Identification of eight differentially expressed TFs and corresponding miRNA targets in comparison to a list of 41 DETFs with predicted targets from miRanda, PITA, and RNA22.