Skip to main content
Fig. 4 | BMC Genomics

Fig. 4

From: Small open reading frames: a comparative genetics approach to validation

Fig. 4

Enrichment of GWAS variants within smORFs. Permutation analysis testing enrichment of SNVs associated with disease/ other traits within smORFs segregated by MAF bins (facets) revealed a statistically significant enrichment among smORFs (Fisher’s method meta-analysis P = 4.96 × 10–5). P values were calculated by comparing the number of observed overlapping SNVs (red) to the number expected based on 10,000 permutations (grey histograms). Meta-analysis using Fisher’s method, H0: no significant enrichment of GWAS SNVs in smORFs. Abbreviation: MAF, minor allele frequency

Back to article page