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Table 2 Odds ratios for type 2 diabetes according to different exposure metrics of night shift work

From: Association of rotating night shift work, CLOCK, MTNR1A, MTNR1B genes polymorphisms and their interactions with type 2 diabetes among steelworkers: a case–control study

Exposure metrics

Control group,n(%)

Case group, n(%)

Model 1

Model 2

OR (95% CI)

OR (95% CI)

Rotating night shift work

 Never

105 (23.3)

32 (12.7)

1.00 (ref)

1.00 (ref)

 Yes

346 (76.7)

219 (87.3)

2.08 (1.35–3.19)

2.00 (1.28–3.11)

Current shift status

 Never

105 (23.2)

32 (12.7)

1.00 (ref)

1.00 (ref)

 Ever

124 (27.5)

69 (27.5)

1.83 (1.12–2.99)

1.86 (1.12–3.08)

 Current

222 (49.3)

150 (59.8)

2.22 (1.42–3.47)

2.08 (1.31–3.30)

Duration of night shifts (years)

 Never

105 (23.2)

32 (12.7)

1.00 (ref)

1.00 (ref)

 1–10

99 (22.0)

49 (19.5)

1.62 (0.96–2.74)

1.80 (1.04–3.12)

 10–20

77 (17.1)

47 (18.7)

2.00 (1.17–3.43)

2.30 (1.31–4.04)

 20–30

118 (26.2)

87 (34.8)

2.42 (1.49–3.92)

2.23 (1.35–3.67)

 > 30

52 (11.5)

36 (14.3)

2.27 (1.27–4.06)

1.51(0.82–2.80)

OR (95% CI) for trend

  

1.24 (1.10–1.39)

1.15 (1.01–1.30)

Average frequency of night shifts (nights/month)

 Never

105 (23.2)

32 (12.7)

1.00 (ref)

1.00 (ref)

 < 3

115 (25.5)

62 (24.7)

1.77(1.07–2.92)

1.64 (0.97–2.76)

 3–8

206 (45.8)

134 (53.4)

2.13 (1.36–3.35)

2.10 (1.32–3.34)

  > 8

25 (5.5)

23 (9.2)

3.02 (1.51–6.02)

2.72 (1.33–5.57)

OR (95% CI) for trend

  

1.41 (1.17–1.69)

1.39 (1.15–1.68)

  1. Model 1: univariate analysis. Model 2: adjusted for age, sex, smoking status, drinking status, physical activity, DASH score, dyslipidaemia, hypertension, liver dysfunction, renal dysfunction and exposure to occupational hazards (high temperature, noise, dust and carbon monoxide (CO)) in each exposure metric. DASH, dietary approaches to stop hypertension. Value in bold: it indicates that it is statistically significant