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Table 3 Physio-chemical properties of HIV-1a and HIV-1b multi-epitope vaccines

From: Employing computational tools to design a multi-epitope vaccine targeting human immunodeficiency virus-1 (HIV-1)

Physicochemical properties

HIV-1a

HIV-1b

Number of amino acids

139

191

Molecular weight

 ~ 14.6 kDa

 ~ 20.5 kDa

Theoretical pI

9.41

9.82

Estimated half-life in mammalian reticulocytes ( in-vitro )

 > 20 h

30 h

Estimated half-life in yeast ( in-vivo )

 > 20 h

 > 20 h

Estimated half-life in E. coli ( in-vivo )

 

 > 10 h

Instability index

49.5

53.27

Aliphatic index

24.53

35.24

GRAVY index

-1.157

-1.064