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Fig. 1 | BMC Genomics

Fig. 1

From: Integration of ATAC-Seq and RNA-Seq reveals FOSL2 drives human liver progenitor-like cell aging by regulating inflammatory factors

Fig. 1

lp-HepLPCs displayed cellular aging. A Generation of human hepatocytes (PHCs)-derived liver progenitor-like (HepLPCs) cells in vitro, followed by ATAC-Seq and RNA-Seq. Senescence was detected by senescence β-galactosidase staining at each stage (N = 3, and scale bar = 200um). B RT-qPCR analyses for the expression of progenitor markers(EPCAM and KRT19) and aging-related genes (IL6, SERPINE1, and P53). (*p < 0.1, **p < 0.01, ***p < 0.001)

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