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Section edited by Igor Rogozin
This section covers comparative genomic studies and novel methods, including phylogenetic analyses, evolutionary genomics and all studies with a cross-taxonomic focus.
Research article
Using whole genome sequence data might improve genomic prediction accuracy, when compared with high-density SNP arrays, and could lead to identification of casual mutations affecting complex traits. For some t...
BMC Genomics 2017 18:618
Published on: 15 August 2017
Research article
Cysteine-rich peptides (CRPs) are gaining recognition as regulators of cell–cell communication in plants.
BMC Genomics 2017 18:610
Published on: 14 August 2017
Research article
Campanulaceae species are known to have highly rearranged plastid genomes lacking the acetyl-CoA carboxylase (ACC) subunit D gene (accD), and instead have a nuclear (nr)-accD. Plastid genome information has been ...
BMC Genomics 2017 18:607
Published on: 11 August 2017
Methodology article
Sickle cell anemia causes severe complications and premature death. Five common β-globin gene cluster haplotypes are each associated with characteristic fetal hemoglobin (HbF) levels. As HbF is the major modul...
BMC Genomics 2017 18:608
Published on: 11 August 2017
Research article
Among the 13 families of early-diverging eudicots, only Circaeasteraceae (Ranunculales), which consists of the two monotypic genera Circaeaster and Kingdonia, lacks a published complete plastome sequence. In addi...
BMC Genomics 2017 18:592
Published on: 9 August 2017
Research article
Studying genetic variation distribution in proteins containing charged regions, called charge clusters (CCs), is of great interest to unravel their functional role. Charge clusters are 20 to 75 residue segment...
BMC Genomics 2017 18:588
Published on: 8 August 2017
Methodology article
Alternative transcription is common in eukaryotic cells and plays important role in regulation of cellular processes. Alternative polyadenylation results from ambiguous PolyA signals in 3′ untranslated region ...
BMC Genomics 2017 18:576
Published on: 4 August 2017
Research article
Members of the Bifidobacteriaceae family represent both dominant microbial groups that colonize the gut of various animals, especially during the suckling stage of their life, while they also occur as pathogenic ...
BMC Genomics 2017 18:568
Published on: 1 August 2017
Research article
Comparative genomics studies investigating the signals of positive selection among groups of closely related species are still rare and limited in taxonomic breadth. Such studies show great promise in advancin...
BMC Genomics 2017 18:555
Published on: 21 July 2017
Research article
Enhancers are DNA regulatory elements that influence gene expression. There is substantial diversity in enhancers’ activity patterns: some enhancers drive expression in a single cellular context, while others ...
BMC Genomics 2017 18:536
Published on: 17 July 2017
Software
The comparison of gene and genome structures across species has the potential to reveal major trends of genome evolution. However, such a comparative approach is currently hampered by a lack of standardization...
BMC Genomics 2017 18:535
Published on: 17 July 2017
Research article
An increasing number of studies are addressing the evolutionary genomics of dog domestication, principally through resequencing dog, wolf and related canid genomes. There is, however, only one de novo assemble...
BMC Genomics 2017 18:495
Published on: 29 June 2017
Research article
Although transposons have been identified in almost all organisms, genome-wide information on mariner elements in Aphididae remains unknown. Genomes of Acyrthosiphon pisum, Diuraphis noxia and Myzus persicae belo...
BMC Genomics 2017 18:494
Published on: 29 June 2017
Editorial
We describe an emerging initiative - the ‘Functional Annotation of All Salmonid Genomes’ (FAASG), which will leverage the extensive trait diversity that has evolved since a whole genome duplication event in th...
BMC Genomics 2017 18:484
Published on: 27 June 2017
Research article
Gene duplication has led to a most remarkable adaptation involved in vertebrates’ host-pathogen arms-race, the major histocompatibility complex (MHC). However, MHC duplication history is as yet poorly understo...
BMC Genomics 2017 18:460
Published on: 13 June 2017
Research article
Despite evidence for adaptive changes in both gene expression and non-protein-coding, putatively regulatory regions of the genome during human evolution, the relationship between gene expression and adaptive c...
BMC Genomics 2017 18:435
Published on: 5 June 2017
Research article
Inferring history from genomic sequences is challenging and problematic because chromosomes are mosaics of thousands of small Identicalby-descent (IBD) fragments, each of them having their own unique story. Ho...
BMC Genomics 2017 18:433
Published on: 5 June 2017
Research article
Normally, one miRNA interacts with the mRNA of one gene. However, there are miRNAs that can bind to many mRNAs, and one mRNA can be the target of many miRNAs. This significantly complicates the study of the pr...
BMC Genomics 2017 18:428
Published on: 1 June 2017
Research article
Borrelia (B.) burgdorferi sensu lato, including the tick-transmitted agents of human Lyme borreliosis, have particularly complex genomes, consisting of a linear main chromosome and num...
BMC Genomics 2017 18:422
Published on: 30 May 2017
Research article
Interferon inducible transmembrane (IFITM) proteins are effectors of the immune system widely characterized for their role in restricting infection by diverse enveloped and non-enveloped viruses. The chicken IFIT...
BMC Genomics 2017 18:419
Published on: 30 May 2017
The editors of BMC Genomics support initiatives that expedite the peer review process and are happy to consider manuscripts that have been reviewed in Peerage of Science. Please indicate in your cover letter if this applies to your manuscript.
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